Opportunity Information: Apply for DE FOA 0002214
The Department of Energy (DOE) Office of Science, within the Biological and Environmental Research (BER) program, offered this discretionary grant funding opportunity (DE-FOA-0002214) to support research aligned with the DOE Genomic Science program. The core purpose of the opportunity is to advance sustainable bioenergy crop development by funding systems biology and genomics-informed studies that can explain and ultimately help improve how bioenergy feedstocks grow and perform in real-world conditions. In practice, the DOE is looking for research that goes beyond single-gene or single-factor explanations and instead uses systems-level approaches to connect molecular processes, environmental stressors, and plant performance outcomes in a coherent, predictive way.
The FOA emphasizes two main research directions. First, it seeks systems-level research that improves understanding of the molecular mechanisms driving bioenergy feedstock productivity when environmental conditions change or become suboptimal. This includes conditions commonly associated with field production such as drought, heat, cold, nutrient limitations, soil variability, or other stress combinations that reduce yields and stability. The intent is to generate deeper, integrated insight into how plants respond at multiple biological scales (for example, gene regulation, metabolism, signaling, development, and physiology) and how those responses translate into growth, biomass accumulation, and resilience. The overall thrust is to build knowledge that can support the design or selection of crops that maintain productivity under the kinds of constraints expected in large-scale, sustainable bioenergy agriculture.
Second, the opportunity specifically calls for systems biology-enabled investigations into the role of microbes and microbial communities in supporting plant productivity and vigor. The FOA highlights the importance of rhizosphere and plant-associated consortia and explicitly includes a broad range of microorganisms such as bacteria, fungi, diazotrophs (nitrogen-fixing organisms), endophytes (microbes living within plant tissues), and viruses. This reflects a recognition that plant performance is often shaped by interactions with microbial partners and communities that influence nutrient acquisition, stress tolerance, disease dynamics, and overall plant health. Applications under this topic would be expected to examine how these complex microbial ecosystems function, how they interact with plant molecular pathways, and how those interactions could be harnessed or managed to improve bioenergy feedstock performance in sustainable production systems.
In terms of administration and scale, this was a DOE Office of Science grant program in the science and technology research and development category (CFDA 81.049). Eligibility was broadly stated as unrestricted, meaning applications could come from a wide range of entity types, subject to any additional eligibility language in the full announcement. The opportunity was published December 23, 2019, with an original closing date of March 9, 2020. DOE anticipated making around 15 awards, with an award ceiling of $3,000,000 per project. Overall, the funding is structured to support substantial research efforts that combine modern genomics and systems biology with environmental and microbial context, aiming to produce actionable understanding that accelerates the development of robust, high-performing bioenergy crops.Apply for DE FOA 0002214
- The Department of Energy - Office of Science, Office of Science in the science and technology and other research and development sector is offering a public funding opportunity titled "Systems Biology Research to Advance Sustainable Bioenergy Crop Development" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 81.049.
- This funding opportunity was created on Dec 23, 2019.
- Applicants must submit their applications by Mar 09, 2020. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $3,000,000.00 in funding.
- The number of recipients for this funding is limited to 15 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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