Opportunity Information: Apply for RFA CA 18 009
This funding opportunity, titled "Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (P01 Clinical Trials Optional)" (RFA-CA-18-009), is a National Cancer Institute (NCI) grant initiative designed specifically for teams that already hold an active NCI P01 Program Project grant. The central goal is to support revision (often called supplement-type) applications that strengthen or speed up the parent P01 by adding a new technology or technical approach that was developed with support from NCI's Innovative Molecular Analysis Technologies (IMAT) program. In practical terms, the NCI is looking for P01-funded groups that can meaningfully extend their existing aims, answer their original questions faster or more effectively, or open up additional high-impact directions by integrating an IMAT-originated tool, platform, assay, instrument, or analytical method into the ongoing program project.
A major emphasis of the announcement is accelerating real-world adoption of emerging IMAT technologies by the broader cancer research community. The revisions supported under this FOA are meant to do more than simply "try out" a new tool; they are intended to incentivize independent validation and demonstrate utility in appropriate, real research settings. By pairing a technology created through IMAT with an established P01 research program, the NCI aims to reduce the lag between method development and widespread use, helping promising innovations move from development into rigorous testing, proof of value, and ultimately broader implementation in cancer research workflows.
Because this opportunity sits within the broader IMAT mission, it also promotes interdisciplinary collaboration. Many breakthrough molecular analysis technologies require expertise spanning engineering, chemistry, computational science, molecular biology, pathology, clinical oncology, and biostatistics. The FOA encourages revision proposals that bring together these disciplines in a targeted way: the technology side contributes a novel capability, while the P01 team contributes mature cancer biology questions, samples, models, and a structured program framework where the technology can be credibly validated and shown to advance discovery.
From an administrative perspective, the opportunity is a discretionary grant mechanism under the U.S. Department of Health and Human Services, National Institutes of Health (NIH), with the NCI as the sponsoring institute. It uses the grant funding instrument and is categorized under health and education activities, with CFDA number 93.394. Clinical trials are optional under this FOA, meaning a proposed revision may include a clinical trial component if scientifically appropriate and consistent with NIH/NCI rules and the parent award's scope, but a clinical trial is not required.
The applicant eligibility list is broad in general NIH terms, but the key practical eligibility constraint is embedded in the purpose statement: the FOA is for revision applications from currently funded NCI P01 program projects. Beyond that, the eligible organization types include many common research-performing entities, such as public and private institutions of higher education, nonprofits with or without 501(c)(3) status, for-profit organizations (including those other than small businesses), small businesses, and multiple levels of government entities (state, county, city/township, special district), as well as federally recognized tribal governments and other tribal organizations, and public housing authorities/Indian housing authorities. This wide eligibility language is standard, but the parent-award requirement effectively narrows who can apply in practice.
In terms of expected support, the FOA lists an award ceiling of $150,000 and anticipates approximately three awards. That scale signals a targeted, selective program aimed at a small number of high-leverage revision projects where a modest infusion of additional funds can catalyze a meaningful technology integration, generate convincing validation data, or remove a key bottleneck that would otherwise slow progress.
Timing details show the FOA was created on December 4, 2017, with an original closing date of September 28, 2018. The overall message of the opportunity is straightforward: NCI wants existing P01 teams to bring in IMAT-developed innovations, validate them in strong cancer research settings, and use them to expand or accelerate the parent program's scientific trajectory, ultimately speeding discovery and encouraging adoption of new tools across the cancer research community.Apply for RFA CA 18 009
- The Department of Health and Human Services, National Institutes of Health in the education, health sector is offering a public funding opportunity titled "Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (P01 Clinical Trials Optional)" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.394.
- This funding opportunity was created on Dec 04, 2017.
- Applicants must submit their applications by Sep 28, 2018. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- Each selected applicant is eligible to receive up to $150,000.00 in funding.
- The number of recipients for this funding is limited to 3 candidate(s).
- Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses, Others (see text field entitled Additional Information on Eligibility for clarification).
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| Funding Opportunity |
|---|
| Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (P50 Clinical Trials Optional) Apply for RFA CA 18 010 Funding Number: RFA CA 18 010 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (U54 Clinical Trials Optional) Apply for RFA CA 18 008 Funding Number: RFA CA 18 008 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (U01 Clinical Trials Optional) Apply for RFA CA 18 007 Funding Number: RFA CA 18 007 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| Revisions for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (R01 Clinical Trials Optional) Apply for RFA CA 18 006 Funding Number: RFA CA 18 006 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $150,000 |
| NIDA Translational Avant-Garde Award for Development of Medication to Treat Substance Use Disorders (UG3/UH3, Clinical Trial Optional) Apply for RFA DA 18 020 Funding Number: RFA DA 18 020 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $1,000,000 |
| Administrative Supplements to NCI Grant and Cooperative Agreement Awards to Support Collaborations with the PDX Development and Trial Centers Research Network (PDXNet)(Admin Suppl - Clinical Trial Not Allowed) Apply for PA 18 496 Funding Number: PA 18 496 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $125,000 |
| Identification of Biomarkers of HIV-1 Pathogenesis and Substance Abuse Comorbidity (R01- Clinical Trial Not Allowed) Apply for RFA DA 18 023 Funding Number: RFA DA 18 023 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Distance Learning and Telemedicine Grant Program Apply for RUS 18 01 DLT Funding Number: RUS 18 01 DLT Agency: Department of Agriculture, Utilities Programs Category: Education, Health Funding Amount: $500,000 |
| Administrative Supplements to NCI Grant and Cooperative Agreement Awards to Support Collaborations with the Drug Resistance and Sensitivity Network (DRSN)(Admin Supp Clinical Trial Not Allowed) Apply for PAR 18 752 Funding Number: PAR 18 752 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $250,000 |
| NCI Community Oncology Research Program (NCORP) Community Sites (UG1 Clinical Trial Required) Apply for RFA CA 18 016 Funding Number: RFA CA 18 016 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Community Oncology Research Program (NCORP) Minority/Underserved Community Sites (UG1 Clinical Trial Required) Apply for RFA CA 18 017 Funding Number: RFA CA 18 017 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| NCI Community Oncology Research Program (NCORP) Research Bases (UG1 Clinical Trial Required) Apply for RFA CA 18 015 Funding Number: RFA CA 18 015 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Approaches to Identify and Care for Individuals with Inherited Cancer Syndromes (U01 Clinical Trial Required) Apply for RFA CA 19 017 Funding Number: RFA CA 19 017 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| HIV/AIDS High Priority Drug Abuse Research (R01 Clinical Trial Optional) Apply for PAS 18 915 Funding Number: PAS 18 915 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: Case Dependent |
| Fusion Oncoproteins in Childhood Cancers (FusOnC2) Consortium (U54 Clinical Trial Not Allowed) Apply for RFA CA 19 016 Funding Number: RFA CA 19 016 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $1,600,000 |
| Administrative Supplements to Cancer Center Support Grants to Strengthen the Research, Training, and Outreach Capacity of the Geographic Management of Cancer Health Disparities Program (Admin Suppl - Clinical Trial Not Allowed) Apply for PA 18 934 Funding Number: PA 18 934 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $250,000 |
| The National Drug Abuse Treatment Clinical Trials Network (UG1 Clinical Trial Optional) Apply for RFA DA 19 008 Funding Number: RFA DA 19 008 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $500,000 |
| NLM Grants for Scholarly Works in Biomedicine and Health (G13 Clinical Trial Not Allowed) Apply for PAR 19 032 Funding Number: PAR 19 032 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $50,000 |
| Administrative Supplements to Cancer Center Support Grants to Strengthen NCI-Supported Community Outreach Capacity through Community Health Educators of the National Outreach Network (Admin Suppl Clinical Trial Not Allowed) Apply for PA 19 035 Funding Number: PA 19 035 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $125,000 |
| Immuno-Oncology Translation Network (IOTN): Immuno-engineering to Improve Immunotherapy (i3) Centers (U54 Clinical Trial Not Allowed) Apply for RFA CA 19 013 Funding Number: RFA CA 19 013 Agency: Department of Health and Human Services, National Institutes of Health Category: Education, Health Funding Amount: $900,000 |
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